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Furthermore, we found silibinin effectively opposes Cdk4 pathway activation at several points and administration as a chemopreventive agent resulted in reduced cell proliferation, increased apoptosis, and reduced adenoma development in Apc −/+ mice.
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They received the support of the papacy and effectively opposed Frederick's reorganization of northern Italy.
After Croesus' fall at the hands of Achaemenian Persia, the cities of Ionia were unable to effectively oppose the latter.
If we want to effectively oppose the forces that threaten Israel from without, we must also oppose the forces that threaten it from within.
"The Taliban's ability to effectively oppose the forces on the ground that are in opposition to the Taliban is degraded and diminished," Mr. Rumsfeld said.
The Bush administration, uncertain that it could effectively oppose China's bid for the 2008 Olympics, has decided to remain silent on the issue.
The issue is not that the Dalai Lama is a poor politician, but that politicians are unwilling to effectively oppose China's colonization of Tibet.
"We have a ruling party that cannot rule and an opposition party that does not know how to effectively oppose the government," Ms. Chen said.
"We are at a loss to find the right recipe to effectively oppose Pegida," Silvio Lang, spokesman of the association "Nazi Free Dresden" admits.
And over the past few years, they have directed their anger not just at President Obama, for messing the country up, but also at the Republican leadership, for being feckless and irresolute and for not effectively opposing the president.
The cities of Lombardy, however, reconstituted themselves, under the leadership of Milan, as the Lombard League, and not only sabotaged the diet at Cremona but effectively opposed Frederick's reorganization of northern Italy.
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