Exact(10)
Fluorescently labeled ETYIKPWWVWL was effectively internalized by all three variants with EC50 of ∼25 nM.
All combinations were effectively internalized by the cells, with slightly better performance when targeting receptors of different endocytic pathways.
These fluorescently labeled MSVs could be effectively internalized by both a human (BxPC-3) and a mouse pancreatic cancer cell lines (Pan02).
These responsive NPs could be effectively internalized by rat vascular smooth muscle cells, which in turn notably potentiated anti-proliferation and anti-migration activities of RAP.
BGNSs@pDA-FA was effectively internalized by cancer cells through folate receptor-mediated endocytosis and generated CO2 bubbles under the acidic environment of the lysosomes, thus enhancing lysosomal membrane permeability (LMP) to release caspase-3 into the cytoplasm, resulting in cancer cell death via an apoptosis-like pathway.
After this period of incubation, images were captured using laser confocal microscopy for the purpose of visualizing the internalization of the developed surface-biofunctionalized ZnS and Zn0.50Cd0.50S QDs. Figure 9B shows that the Zn0.50Cd0.50S (A) and ZnS (B) conjugates were effectively internalized by HEK293T cells.
Similar(50)
Staining with Prussian blue confirmed that the nanocarrier could be effectively internalized into HeLa cells.
The staccato style, sometimes merely hasty and melodramatic, is effectively internalized as Corey's mother suddenly collapses and dies: Then comes the first blow.
DNA/antibody PLL complexes were effectively internalized into Molt 4 cells after 4 h incubation at 37°C and showed significantly higher in vitro transfection efficiency than DNA/PLL complexes and DNA/Lipofectin™ formulation due to the targeting effect of receptor-mediated endocytosis induced by anti-JL1 antibody.
The designed microspheres allow the encapsulation and slow release of oligonucleotide/PEI solid complexes that should be effectively internalized inside cells.
The cellular uptake result showed that the proposed fluorescent theranostic nanomedicines could be effectively internalized into HepG2 cells and release DOX into the cell nuclei.
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