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A legislative body cannot legislate wisely or effectively in the absence of information respecting the conditions which the legislation is intended to affect or change; and where the legislative body does not itself possess the requisite information-which not infrequently is true-recourse must be had to others who do possess it.
Interestingly, despite absence of Neurog1, hair cells strongly express Neurod1 [17], suggesting that hair cell specific factors such as Atoh1 are also able to upregulate Neurod1 expression and can do so more effectively in the absence of Neurog1.
Moreover, the persistent single-strand breaks (SSB) formed upon PARP-1 inhibition cannot be repaired effectively in the absence of functional BRCA1 or BRCA2, resulting in accumulation of chromosomal abnormalities, cell cycle arrest and apoptosis [ 8, 9].
However, we found that ADF could activate feeding as effectively in the absence of mod-5 as in its presence, suggesting that serotonin from ADF directly activates SER-7.
Complexes of LBP and bacterial constituents may then easily bind to membrane CD14, a process that occurs much less effectively in the absence of LBP, although alternative mechanisms of LPS-transfer to membrane CD14 may also exist [ 36].
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Imagine with horror, for instance, the effect that this storm would have had without the ability to foresee its power, its path, and its likely effects, and to communicate the information quickly and effectively — even in the absence of the sort of adequate long-term preparation that science recommended and that politics spurned (as reported by Mireya Navarro in the Times just last month).
Finally, people can't be effectively managed in the absence of relevant performance information information that can and will be acted upon.
The mechanisms are complex, but they involve a "backstop". In theory, this could mean that a temporary commitment to a customs union meant to address the Northern Ireland problem might effectively become, in the absence of a further deal, a permanent one for all of Britain, which could only get out of it with the E.U.'s consent.
Air mass transport with new and old airplane models mixes the global sphere more effectively than in the absence of new models". I have been following Bejan's work particularly with an eye to what it might tell me about Apple's design evolution.
Those jobs are probably more easily and effectively done in the absence of crazy taboos.
We hypothesized that cortical motor commands cannot be effectively generated in the absence of kinaesthetic feedback.
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