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"What you need to have," he said, "is something that effectively disrupts the market".
Accumulating evidence indicates that the CRISPR/Cas9 system effectively disrupts HBV genome, including cccDNA, in vitro and in vivo.
SDS is a potent anionic detergent that very effectively disrupts protein-protein interactions [2].
Our results show that Hsp90 inhibition effectively disrupts these as well, with ganetespib potently degrading EGFR and blocking both IL-6- and FLT3-mediated activation of STAT proteins.
We previously demonstrated that heart muscle-specific expression of a nuclear dominant negative CELF protein in transgenic mice (MHC-CELFΔ) effectively disrupts endogenous CELF activity in the heart in vivo, resulting in impaired cardiac function.
Taken together, these results suggest that a peptide encompassing the first 29 amino acids of PKAc effectively disrupts the AKIP 1A-PKAc interaction and decreases nuclear import of PKAc.
Similar(48)
The authors use the drug nocodazole to effectively disrupt the microtubule cytoskeleton and observed no effect on the polarization of the PCP components.
Interestingly, activation of TRPC3 channels by GSK effectively disrupted colocalization of the signalling proteins and a similar effect was initiated by AngII (see Supplementary material online, Figure S9 ).
The symbiosis is effectively disrupted by hollow, blustery background music that turns out to be the theme from the 2000 movie "The Patriot," composed by John Williams.
When he is in spaces where he can catch and quickly finish, it's an indication that Gerald Wallace and Williams are finding avenues to the rim off the dribble and that the Nets' baseline screens are effectively disrupting the defense.
Rather than asking how to support the Karzai government, we should be asking how, given the realities of Afghanistan, we can most effectively disrupt Qaeda operations and kill Qaeda leaders.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com