Peng et al illustrated that pooling RNA samples was a cost-effective tool for discovery science which yielded results representative of group by group differences, as long as the groups are sufficiently different and defined [21].
Exome and target sequencing studies have shown to be an effective tool for the discovery of new ASD genes.
These results demonstrate that Illumina sequencing technology can be an effective tool for gene discovery in non- model organisms.
The potential of GWAS as an effective tool for QTL discovery, when coupled with sufficient marker density and reliable genetic map information, was evident from the high number of QTLs (up to 50) that were mapped consistently across environments.
Target validation studies for all BC subtypes have largely employed established BC cell lines, which have proven to be effective tools for drug discovery.
Given the lines of evidence suggesting that BC cell lines are effective tools for drug discovery, we assessed the similarities between triple-negative BCs and cell lines, to identify in vitro representatives, modelling the diversity within this BC subtype.
HGTector is an effective tool for initial or standalone large-scale discovery of candidate HGT-derived genes.
This work demonstrates that RNA-seq is a useful and effective tool for de novo transcriptome assembly and discovery of candidate genes underlying host genetic resistance to pathogens, even in a non-model species without genome and complete EST databases.
Furthermore, the in silico data mining approach used here for evaluating transcriptional consequences of the detected aberration shows the power of utilization of previously published gene expression data providing a rapid and cost-effective tool for the discovery of new biomarkers.
LinkedIn became an effective tool for business staff recruiting.
