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The most cost effective screening strategy seems to be contingent screening (cost effectiveness ratio $C26 833 per case of Down's syndrome with a high risk cut-off value of 1 in 30).
In conclusion, herein we developed a simple and effective screening strategy to identify chemical compounds modulating SG assembly/disassembly.
Diagnosis usually occurs after metastatic spread, largely reflecting vague symptoms of early disease combined with lack of an effective screening strategy.
Lung cancer is still diagnosed at a late stage disease, mainly due to the lack of early disease symptoms and the absence of an effective screening strategy.
However, cell phenotype-based screening has drawbacks, include: 1) the requirement of engineering a separate reporter cell line, 2) most screens depend on a single or a limited number of surrogate readouts, 3) toxic components are hard to filter out, 4) many diseases lack good "drug" targets for developing an effective screening strategy.
These results established our virtual screening protocol as an effective screening strategy for the discovery of potent and selective inhibitor of EBNA1, and provided a novel scaffold for future design of more potent and specific EBNA1 inhibitors.
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However, not all use effective screening strategies.
Since skepticism with the pap smear arose a few decades ago, doctors like Jerónimo have been working tirelessly to find more effective screening strategies.
Investigative efforts to establish effective screening strategies for earlier detection and mortality reduction have been unyielding.
Clinical risk factors associated with the acquisition of biliary fungal infections are important for reasonable and cost effective screening strategies.
Due to the asymptomatic nature of early HCC and lack of effective screening strategies, most patients (>80%) present with overt advanced disease.
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CEO of Professional Science Editing for Scientists @ prosciediting.com