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Cyclosporine is generally considered the most effective of these agents, providing a rapid response [ 14].
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An understanding by physicians of the patient's feelings and concerns towards prevention are important for more effective use of these agents.
The cumulative body of research regarding AP use in youth demonstrates that there are gaps in knowledge regarding safe and effective use of these agents.
Inhibition of intracellular AKR1C3 activity as measured using a 11 β-PGD2-ketoreductase TLC assay for representative inhibitors in each of these classes identified low n M IC50 values (3 68 n M) clearly demonstrating the effective penetrance of these agents into cells.
The most effective of the agents identified, thiostrepton, significantly enhanced ATO-mediated cytotoxicity and apoptosis in a panel of melanoma cell lines.
For as science and technology advance, there will be need to iteratively re-assess current perspectives and definitions of what constitutes weaponizable biology, and to engage international discourse toward more effective, efficient guidance and governance of these agents and the activities and entities that are capable of producing them.
All of these agents were effective in solubilizing brain Aβ, although BC was the most consistent across the range of AD brain tissue samples tested.
Not all of these agents were effective.
Whether any of these agents are effective in the treatment of irritable bowel syndrome is controversial.
Unfortunately, none of these agents proved effective in adhesion reduction [ 25].
An RSI protocol using fixed ratios of these agents delivers effective pre-hospital trauma anaesthesia.
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