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If science shows a vaccine to be safe and effective, issues such as customs, shipping or refrigeration cannot delay it.
The most effective issues were among the least used.
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A terrorist attack that claimed lives would hand the People's Party an effective issue with which to hurt him.
The calculation here is that accusing Democrats of wanting to "raise" taxes will be an effective issue in the president's re-election campaign.
Should they indeed be a central topic this fall, corporate abuses could be an unusually effective issue for Democrats, because this is likely to be an election with a relatively low voter turnout.
When a new bond is put into effect, it can be written to cover losses that have occurred but are undiscovered before the effective issue date of the bond.
Mr. Boehner's demand, delivered the day after a dramatic hearing by a House committee, signaled that Republican leaders intend to continue portraying the attack as a major failure by the administration as well as a potentially effective issue against former Secretary of State Hillary Rodham Clinton if she runs for president in 2016.
Mark Landler writes that the move signals that "Republican leaders intend to continue portraying the attack as a major failure of the administration as well as a potentially effective issue against former Secretary of State Hillary Rodham Clinton if she runs for president in 2016".
So far, however, it's too soon to say what will stick, especially since the most powerful (and probably effective) issue uniting Democrats at the moment is hatred of Trump.
Last week I moderated a panel, "From Campaign to Governing: Twitter by the Issues" at Jeff Pulver's #140conf at the 92 Y in which we discussed how the momentum from 2008 fissured into smaller, nimble and effective issue groups in the digital sphere.
There are sessions with mothers about health and effective parenting issues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com