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Compensatory mechanisms are effective initially but, eventually, they can have deleterious effects.
Treatments targeting various components of this pathway are ongoing, and are often effective initially in defined subgroups of patients.
This hormonal therapy is effective initially, as assessed by the decline in prostate specific antigen (PSA) levels.
Services like Blue Apron may have been effective initially through word of mouth and promotions, but as it gets more and more expensive to acquire customers the company has to figure out ways to keep them for a longer amount of time in order to earn back that spend.
Therefore, it is not surprising that at least three of the conventional medical treatments that were found to be "effective" initially were later found to be so dangerous that the drugs were withdrawn from medical use.
While androgen withdrawal therapy is often effective initially, most cases progress to the much more aggressive androgen-independent phenotype.
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It is cost-effective: initially screening many conditions by low-cost, but non-specific profiling test methods, and then pursuing selected conditions by more informative methods.
This "drift", as experts call it, rendered the current vaccine far less effective than initially expected.
This "drift," as experts call it, rendered this season's vaccine far less effective than initially expected.
Salvage surgery after alectinib treatment may be safe and effective for initially unresectable NSCLC harboring ALK-rearrangements.
He also came into power, of course, with both the House and the Senate under Democratic Party control, but that Democratic majority ultimately proved less effective than initially anticipated.
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