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Interestingly, this study showed that CRT could be equally safe and effective independently of the patient volume treated in each contributing centre.
Letrozole was effective independently of HER2 expression status, although the greatest difference between letrozole and tamoxifen was seen in tumors that were HR+ and HER1/2+.
Primary PCI is effective independently of the electrocardiogram pattern (that is, with or without ST-segment elevation) [ 4], suggesting a poor predictive value of the electrocardiogram in identifying patients who may benefit from coronary intervention.
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Demographic processes modulate genome-wide levels and patterns of genetic variation via impacting effective population size independently of natural selection.
Results provide clear evidence that both Fe0 and sand were independently effective for the discoloration of MB.
Double or triple shRNA vectors were independently effective in simultaneously reducing HCV replication, CD81 expression, and E2 binding.
By simulations with Newell's car-following model and the Comprehensive Modal Emissions Model (CMEM), we demonstrate that such a strategy is effective and robust independently as well as cooperatively for different market penetration rates of IVC-equipped vehicles and communication delays.
In addition, at 250 µM, BP7033Br ALK is effective on cells independently from the estrogen-receptor status.
The disadvantage of serially dependent recognition is the possibility that it might work against temporal integration mechanisms (e.g., of motion, orientation, color, faces, etc); temporal integration would be most effective with more independently coded patterns.
The same study [ 78] also reported that overexpression of RAD51 suppresses defects in DMC1 mutants, indicating Rad51 can carry out effective homology searching independently.
However, by considering only those drug combinations where the individual drugs involved are also independently effective antileishmanial agents, this limitation can be potentially overcome.
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