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But the fact is, it does work when people do it". A Cochrane Review that combined studies looking at AA and other 12-step programs found 12-step programs weren't any more effective in decreasing alcohol abuse compared with other treatments, although researchers found limitations with some of the studies.
While many single site studies and 2 meta-analyses [ 9, 10] indicate that naltrexone is more effective than placebo, there have also been 2 multisite studies and 1 single site study in which naltrexone was not found to be effective in decreasing alcohol consumption [ 11- 13].
Alcohol misuse by young people is a serious concern, yet few prevention strategies exist which are effective in decreasing alcohol use and related harms, and there are no programs which integrate universal and selective approaches to maximize the prevention outcomes at the population level.
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Couple's treatments that emphasize relationship issues have proven effective in treating depression in both partners, as well as in decreasing alcohol and substance abuse and violence in the male partners.
Recently, a number of studies have identified self-employed Protective Behavioral Strategies (PBS) as effective in decreasing the level of alcohol-related harm among young people.
An open-label study found that fluoxetine was effective in decreasing both depressive symptomatology and alcohol consumption in adolescents with MDD [ 20].
Indeed, Saitz proposed that enhanced brief intervention strategies may be effective in decreasing the direct complications associated with unhealthy alcohol use [ 11, 39].
A comprehensive assessment of alcohol use during pregnancy is advocated to identify high risk drinking patterns, discuss prenatal alcohol exposure and offer effective counseling to decrease alcohol intake [ 56- 58].
A recent study comparing Botox with a placebo found that it was nearly three times as effective in decreasing sweating.
Loxoprofen-Na was especially effective in decreasing c-Fos expression.
AH.FC.09 appears to be the most effective and AH.FH.09 the least effective in decreasing cell viability.
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