The German general staff, by 1918, had developed new tactics and command structures that proved effective in conditions of modern industrial war, leading to victory in the east and brilliant, if temporary, successes in the west.
Taken together, the above literature suggests that zinc has an essential role in immune function and protecting against infectious disease, but zinc supplementation is probably only effective in conditions of zinc deficiency, and only for certain infections.
Therefore, TβRI inhibitors may be effective in treating conditions of skeletal fragility.
Although irradiation with UV-light of 254 nm is a simple method, it is only effective in limited conditions since the extent of DNA modification by UV light decreases with the square of the distance between the UV light source and the irradiated agent.
Vaccine prequalification is a WHO-led activity intended to ensure that vaccines purchased by UN procurement agencies will be consistently safe and effective under conditions of use in national immunization programs in low- and middle-income countries (LMICs).
Similarly, retroviral vectors might also be less effective in hypoxic conditions, since upon activation of the PERK kinase under hypoxia, eIF2 α gets phosphorylated, leading to overall inhibition of translation (Koumenis et al, 2002).
Such strategies may be effective in inflammatory conditions associated with local infiltration of neutrophils, for example chronic sinusitis, inflammatory bowel disease and rheumatoid arthritis.
Most of these factors are effective in clinical conditions.
The open-field behavioural assay has been effective in identifying broader conditions of ill health in mice, including cardiovascular and metabolic dysfunction [ 16, 17], but provides symptomatic information rather than mechanistic insight.
The anti-inflammatory and immune modulating functions of corticosteroids are effective in the treatment of conditions such as asthma, allergic reactions, eczema, psoriasis, rheumatoid arthritis, and inflammatory bowel disease.
