In contrast, if washed PLTs are effective for only a short time after washing, this would indicate that BRMs that accumulate in PLT components are responsible.
In our patient, treatment with ceritinib proved to be effective, however, for a short time only.
The relatively low effective mobility for C 8-BTBT is mainly due to the short channel length of 20 μm; the contact resistance generally dominates over the observed effective mobility for a short channel length [9].
Therefore, from a pathophysiological point of view, all of the above-mentioned therapeutic strategies may be effective only for a short period of time, if at all, but are doomed to fail in the long term [ 44, 53].
Some experts contend that mice get used to the beep after a short while, making them effective only for a short time.
With the large-scale cracking of accounts that rely on CAPTCHAs, a healthy market for cheap accounts as well as the complexity of CAPTCHAs now reaching their limits of usability, it might finally almost be time to bid farewell to a security solution that has never been popular and was only effective for a very short period of time.
For example, the contribution of excitotoxicity mediated by glutamatergic NMDA receptors to ischemia-induced cell death is well appreciated, however, blockers of these receptors are not well tolerated and are only effective for a very short time following the onset of ischemia [11].
Despite variability among studies, results suggest that exercise is effective for producing a short-term energy deficit and that individuals tend not to compensate for the energy expended during exercise in the immediate hours after exercise by altering food intake.
Sugimoto et al. found that the production of TNF-α and IL-6 in neonatal monocytes under constitutive and LPS-stimulated conditions was substantially reduced after pre-treatment with a clinically effective MgSO4 concentration for a short time, and this effect did not influence the viability or phagocytic function of monocytes20.
Birds learn quickly and are able to adapt to changing conditions, so a seemingly effective solution may only work for a short time.
