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Results show that the effect of combined TNF-α/CyD1 NiMOS resulted in a stronger, more effective decrease in expression compared with single siRNA treatment of TNF-α alone, but less powerful than the effect of CyD1 administration potentially due to dilution effect with TNF-α NiMOS.
As shown in Figure SP1G, the inhibition of RyR types 1 and/or 3 exhibits the most effective decrease of NAADP-induced signalling while inhibition of RyR2 has no effect.
induced an effective decrease in HCV RNA [ 13, 21- 23] and the anti-viral effect was similar to that reported for pegylated interferon monotherapy [ 23].
The small plastic strain associated with the loops invokes an effective decrease in the moduli that describe the linear relation between the applied stress and the total strain.
Numerical calculations under plane stress assumption show that dissipation enables an effective decrease in the energy needed for the phase transformation to occur.
Concerning cyclic tests, in addition to observations on the monotonic tests, the increase of strain rates leads to an effective decrease of the connections' ductilities.
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Availability of drugs that are likely to be effective decreases as drug resistance becomes more extensive.
The probability that surgery is cost effective decreases to 0.77 if patients who return to proton pump inhibitors have worse GORD symptoms than before surgery (scenario 7).
We have previously demonstrated that complexes of olive biophenols with β-cyclodextrin were effective decreasing the oil bitterness and preserving from decomposition during storage [ 8].
The introduction of the seven valent conjugated pneumococcal vaccine in the USA has shown to be very effective decreasing the incidence of invasive pneumococcal disease in children.
In the graphs, the probability that thiazide diuretic is cost-effective decreases as the CE threshold increases.
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