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This was a conservative approach because it goes against the most effective arm (TiC).
Documentation collected for the hard endpoints of requiring aids for walking (DSS 6), for restriction to bed with effective arm use (DSS 8) and death from multiple sclerosis (DSS10) left little ambiguity.
Thus, the addition of further complexity in an ACT featuring response-adaptive randomization of participants to what appears to be the more effective arm or explaining fixed-interim analysis could appear to increase the complexity of informed consent decisions [ 31].
Moreover, there is focus on the issue of resources; how we can identify the most effective arm lymphedema treatment and achieve the desired clinical benefit with minimal patient inconvenience.
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For truly effective arms, they showed that the bias in the estimated treatment effects on the definitive outcome at the final stage analysis was of no practical importance.
Mr. Booker's supporters view Mr. James's extensive support by city workers as little more than effective arm-twisting by the head of the Newark's vast political machine.
The current tensions could just be another example of Mr Putin's effective arm-twisting in trade negotiations with smaller nations rather than the pointless bullying that it appears to be.
It came thanks to a combination of electoral pressure in the East and highly effective arm-twisting by the West German chancellor, Helmut Kohl.The author comes across as more at home with her sources than with the region's wider history.
We have tried with reasonably good will to fashion effective arms-control agreements, but Sec.
Only an effective arms embargo and a multilateral intervention to create safe havens for civilians will stop the slaughter.
A nuanced assessment of the I.A.E.A. report was published by the Arms Control Association (A.C.A ., a nonprofit whose mission is to encourage public support for effective arms control.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com