The main finding of this study, relying for the first time on experimental screening designs to evaluate chromatographic isotope effects, is that the most effective approach to avoid a chromatographic isotope effect is through the use of non-deuterium-labeled reagents in AIDA.
Results confirmed that the most effective approach to avoid chromatographic isotope effect is the use of N or C labeling instead of deuterium labeling, while chromatographic parameters had no general influence.
A more effective approach to avoid degeneracy is resampling.
We propose that targeting cAMP/PKA to boost proteasome activity in a sustainable manner could offer an effective approach to avoid early accumulation of SUb proteins and later caspase activation, and TAU cleavage, possibly preventing/delaying AD neurodegeneration.
Removal of all individuals of each species at this early stage of the invasive process is a cost-effective approach to avoiding other significant invasions of the natural habitat in the long term.
Blocking the CGRP receptor may be an effective approach to migraine relief while avoiding the vasoconstrictive effects associated with triptans.
Therefore a complete transvenous approach to avoid thoracotomy was attempted.
We took this conservative approach to avoid overextending the tibia.
Thus, an effective approach to diminish telomere loss would be of great importance to avoid the accumulation of replicative senescent T cells with aging.
Thus, adequate immunosuppressive treatment, avoiding minimization strategies and reinforcing educational actions to prevent noncompliance, is at present an effective approach to combat the progression of fibrosis.
