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Current FDA approved disease modifying therapies for MS such as beta interferon, glatiramer acetate and natalizumab are only partially effective and cause side-effects.
Overall, effectiveness trials have shown that second-generation antipsychotics are as effective and cause fewer extrapyramidal side effects relative to first-generation drugs, but come with new metabolic side effects.
Consequently, anti-inflammatory drugs may be few effective and cause serious side effects when they are orally administered [ 10, 11].
For many non-localized cancers, chemotherapies are used which can be effective, however specific delivery would be more effective and cause fewer side effects [ 5- 8].
The majority of BBT users (as compared to nonusers) in the current investigation believed that BBT products are safe, effective and cause fewer side effects as compared to prescription medications.
Santos followed that statement with an appearance on Colombian television yesterday, 11 May, where he said "We must find strategies [to combat cultivation] that are more effective and cause less harm to the environment and public health".
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It was seen as more effective and causing fewer side effects than Western treatment.
The FDA revoked its approval of Avastin as a treatment for metastatic breast cancer after clinical trials showed it was not effective and caused potentially serious side effects, the New York Times wrote.
PPRHs against the promoter sequence were the most effective and caused a decrease in survivin mRNA and protein levels.
In addition, the application of traditional pesticides is not effective and causes high residue level or negative impact on the environment.
Finally, the mechanism of doxorubicin-mediated apoptosis in retinoblastoma cell line (Y-79) was investigated which demonstrated that the mitochondrial pathway is activated and that the FA-conjugated DOX-CNPs are most effective and causes enhanced release of cytochrome c as well as the activation of downstream caspases to assist in apoptosis.
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