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Rituximab (R), a chimeric anti-CD20 monoclonal antibody, is well tolerated with limited toxic effects and is effective alone or in combination with chemotherapy in the treatment of indolent and aggressive forms of NHLs, including FL [ 6– 8].
TPT is effective alone with cytotoxicity effects less than the doxorubicin (a classical AML drug) group (Additional file 1: Figure S1) or when combined with other drugs for AML, such as lapatinib, paclitaxel.
Whether trastuzumab would be effective alone in these patients (without the potential side effects of standard chemotherapy regimes) deserves investigation.
This pilot study compared the effects of three interventions targeting those components individually and in combination on stress-related eating, perceived stress, and weight loss to determine whether the two intervention components are effective alone or are more effective when combined.
Although trastuzumab can be effective alone, cancer cells eventually develop resistance to it, causing a relapse or progression of the cancer.
These data suggest that resveratrol, although effective alone, can enhance the antitumor activity of TRAIL in prostate cancer.
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Among therapeutic approaches, psychotherapeutic interventions may be effective, either alone or associated with pharmacological therapies.
Recent clinical studies recommend calcium channel blockers (CCBs) as effective treatment alone or in combination with other medications.
Although gemcitabine was minor effective, cabozantinib alone or combined with gemcitabine strongly reduced the expression of CD133 and c-Met.
The system would only be effective if Ran alone crossed NPCs more slowly than RanGTP·NTR complexes.
The drug combination also proved more effective that pregabalin alone and more effective than celecoxib alone, except for patients with LANSS score <12.
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