However, a peptide containing the RGD motif from the human PSG9 N domain binds to a receptor on a promonocytic cell line suggesting that some human PSGs may effect their functions through an integrin-type receptor [ 18].
Recent studies have suggested that tumor cells secrete tumor-derived factors that induce STAT3 activity within neighboring APCs, effecting their maturation and function [8].
Designing Safer Chemicals: Chemical products should be designed to effect their desired function while minimizing their toxicity.
While these patients also reported other symptoms on the PHQ-14, it was the localised joint pain, which had the greatest effect on their functioning.
21 In line with the theory of "use it or lose it", 22 participating in cognitive stimulation may activate neurons, which can in turn improve and have a protective effect on their functioning.
High density lipoproteins (HDL) have an antiatherogenic effect reflecting their function in reverse cholesterol transport to the liver and their anti-oxidant properties[6].
Among different plant species, soybeans are reported to have a higher average ratio of Nonsyn/Syn SNPs than Arabidopsis and rice, with larger effect SNPs in 4,648 genes that have greater effects on their functions [ 35].
In addition, the significant correlations in our sample between negative symptoms and impaired ToM and neurocognition indicate the challenges of separating their effects on functioning.
Thousands of proteins are subjected to posttranslational modifications that can have dramatic effects on their functions.
While age-related memory decline may not be a harbinger of Alzheimer's disease, for many people it has a real effect on their function, and safe interventions may be in sight.
