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The similar gene arrangement is surprising, given that the Sulfolobales and Halobacteria are not closely related and that the AICAR formyltransferases PurP and PurH1 are structurally and mechanistically unrelated despite effecting the same biosynthetic step.
Such findings argue against the plausibilty of a particular variant always effecting the same functional consequence, unless the true disease effect is driven by an unknown factor in cis, which is coincident in a subgroup of alleles.
Similar(58)
In effect, the same would happen here.
God and the heartless bureaucracy are in effect the same.
What are the side effects?" The same question disturbs many parents of soccer players.
The newest Latin American companies operate, in effect, the same way, critics like Professor Leeds contend.
This is in effect the same tax deduction "for the purchase of health insurance" that you oppose.
I don't do visual effects the same way.
In effect, the same genes have different effects depending on who they are talking to.
They want, in effect, the same things Beethoven wanted.
To avoid learning effects, the same stimuli occurred only once.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com