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Thus, humankind's constant modification of its habitat and customs throughout history has also effected profound changes within its pathogen community.
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Current evidence suggest that lipids are not mere energy-providing metabolites but can effect profound changes via various signaling pathways.
Effecting profound change is neither simple nor speedy.
Mr Modi seems to expect he will be in office for more than one term, which would mean having time enough to effect profound change.
Themes like the individual's ability to effect profound societal change, as evidenced by this scene of Bumblebee punching a military drone unit in the face.
Russia's foreign minister, Sergei Lavrov, said "precedence should be given to ending the violence and continuing efforts to effect profound political and socioeconomic changes in Syria without delay".
The development of the HRA has begun to effect a profound change in British legal thinking, one that is long overdue.
In a short statement, he said: "We've witnessed brave people of all ages coming together to effect a profound change in their country.
In cities with significant existing restrictions on housing beyond zoning, the measure's effects could result in profound changes to the development approval process.
Given that coastal systems will be at the forefront of climate change effects, they may undergo profound changes in the near future with associated implications for ecosystem services.
"This provides us with another example of how the strong interactions exerted by sea otters on their invertebrate prey can have cascading effects, leading to unexpected but profound changes at the base of the food web," said Tim Tinker, a member of the research team at Santa Cruz.
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