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Trial sequential analysis suggested that as of 2007 (after the ninth trial), sufficient evidence had accrued to demonstrate that the likelihood of finding a treatment effect was too low to justify further data collection.
Similar(59)
The floor effect is too low for all scales except (RP and RE).
"We aren't having that debate right now about new technologies because the level of understanding of their effects is too low.
Underpowered studies in this regard suffer from a major problem: the chance to detect valid effects is too low to be reliable in any kind.
The 1.2 × 3 treatment had no effect, indicating that the dose was too low.
This suggests that even though the current through TRPC6 had increased, there was no effect on Ca2+ because the extracellular source was too low and there was no secondary source.
The activity toward CA of the M57L mutant enzyme was too low to evaluate the effect of L-cysteine.
The observed incidence of antibodies to golimumab was too low to evaluate their effect on clinical efficacy and safety.
Moreover, protein-protein interaction (PPI) networks were not employed for predicting adverse drug interactions until Lucas Brouwers et al. presented the contribution of PPI networks to drug side-effect similarities [ 15]; however, the prediction precision was too low (= 0.298) to be of practical significance.
The number of participants with history of steroid use (6 participants) was too low to have any significant effect.
However, the statistical power was too low to exclude a minor effect from age.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com