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This beneficial effect was not substantiated in the group of patients with high VD as assessed with the pan-endothelial marker CD31.
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However, these effects are not substantiated in a recent meta-analysis of multiple trials with data available for HER2 and TOP2A [ 8].
We hypothesized that fast-track discharge has a positive effect on family satisfaction which was not substantiated in our study.
Nevertheless, in a combined analysis of the data from the same trial and a supplementary trial where metformin was given in combination with sulfonylureas, the effect of metformin on cardiovascular outcomes was not substantiated, due to increased cardiovascular mortality in the combination group (HR 1.96) (2).
In some cases, there was an assumed cause-effect relationship between AGEI outputs and positive trends, which was not substantiated by clear evidence.
This mistaken-identity theory was not substantiated, and it did not hold up at trial.
Although an interesting proposition, this claim was not substantiated.
The case was investigated by the police but was not substantiated.
This hypothesis was not substantiated.
Our second hypothesis was not substantiated.
However, this statement was not substantiated with fertility results.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com