Indwelling pleural catheters (IPCs) allow ambulatory fluid drainage and are free from side effects, the need for hospitalisation and costs of pleurodesis.
Pentostam and Glucantime are first-line drugs for both VL and CL; however, they present several limitations, including severe side effects, the need for daily parenteral administration, and the development of drug resistance.
With the development of interferon free, all oral, potent antiviral agents with less adverse effects, the need for screening individuals and successfully treating at-risk CHC patients becomes increasingly more important and possible.
The effects on eCrCl are likely to result in a beneficial effect on the need for RRT when tested in a larger trial.
Two recent meta-analyses have found a beneficial effect associated with sodium bicarbonate in terms of a decrease in AKI incidence, whereas there was no effect on the need for RRT and in-hospital mortality [130, 133].
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We also computed the aggregate effect on the need for tracheal intubation per se, as it was a common definition of NIV failure in the included studies.
Finally, the profiles for models whose predictive uncertainty estimates are not reliable provide clues to that effect without the need for comparison to an external test set.
The preventive or curative administration of NAC for AKI has not demonstrated any beneficial effect concerning the need for RRT and reductions in mortality [129, 189 192].
Halepete et al. (2009) identified a positive effect of the need for uniqueness on attitude towards customization of products that have discernible preferred differences, such as apparel.
