Sentence examples for effect the localization of from inspiring English sources

PML Ib not only showed a predominant cytoplasmic localization, it also significantly effected the localization of the PMLI isoform raising the intriguing possibility that cPMLΔ5&6 may also effect the localization of predominantly nuclear PML isoforms during viral infection.

Because the nuclear localization sequence (NLS) for PML is located on exon 6 it was of interest to determine how the deletion of exons 5&6 effected the localization of PMLIb.

This result also suggests that the anchoring domain has significant effect on the localization of enzymes in the cell wall.

Hitherto unavailable numerical results pertaining to the influence of this effect on the localization of buckling patterns and the ensuing shear crippling instability are also presented.

Subcellular fractionation and mitoplasting with or without proteinase K treatment was performed to ensure that APEX and other tags had no effect on the localization of the proteins (Fig. 4G).

We next analyzed whether binding and internalization of Stx and ricin had an effect on the localization of flotillins.

The dsRNAs were then expressed, corresponding to each of the selected genes in the wing discs, and the effect on the localization of these membrane proteins determined.

Deletion of the PCI domain of UFBP1 had almost no effect on the localization of the protein, while deletion of the signal peptide resulted in an exclusive nuclear localization (Figure 4A).

Mutation of residues "downstream" of the PEXEL motif had minimal or no effect on the localization of a STEVOR protein [10], highlighting the relative importance of its PEXEL preceding sequence.

To determine whether loss of rab-5 had an effect on the localization of APL-1, we used RNAi to knock-down rab-5 expression in an integrated APL-1 GFP APL-1 GFP strain on thexpressionstrain rrf-3(pk1426) backgronnd.

The aim of the present simulations is to elucidate the effect of the localization of the enzymes.