In deterministic sensitivity analysis, increasing the frequency of injections and follow-up visits had a strong effect on the cost effectiveness.
While the alternative scenarios described above (Table 7a c) had only relatively small effects on the cost effectiveness of ART, the impact of a pessimistic assumption about future treatment effect was more substantial.
This shows that social influence can have significant effects on the cost effectiveness of treatment policies.
The direct and indirect costs associated with pneumococcal disease are high, thus vaccine serotype infections prevented by herd protection and cases caused by non-vaccine serotypes have strong effects on the cost effectiveness of pneumococcal vaccination in NIPs.
The direct and indirect costs associated with pneumococcal disease are high, thus herd protection and infections caused by non-vaccine serotypes both have strong effects on the cost effectiveness of pneumococcal vaccination.
In our model, the additional infections averted by preventing one case (ie the herd effect of interrupting disease transmission) were taken into account using a simplistic factor of 0.5 for all cases averted; as soon as clinical evidence is available that allows evidence-based dynamic modeling of the indirect effect, the cost-effectiveness of such an approach will warrant additional study.
Given the potential financial effects of dabigatran, the cost effectiveness analysis by Pink and colleagues is timely and relevant.
The aim of this larger study is to assess the effect, the costs and the cost effectiveness of the waiting time in patients awaiting TJR.
These effects, if included, might have pulled the cost effectiveness in a more favourable direction.
Although it often causes a few side effects, the cost-effectiveness and low-toxicity of zinc made it a good catalyst for organic reduction and synthetic reaction.
The results suggest that depending on the combinations of differing assumptions on the possible long-term vaccine effects, the cost-effectiveness profile of each PCV may vary widely.
