Sentence examples for effect similarities from inspiring English sources

In subsequent studies, the authors reported prediction methods using integrated similarity measures including interaction profile similarities, adverse effect similarities, and target similarities [9].

It seems that chemical structure similarities are correlated with pharmacological effect similarities to some extent.

The similarity score is referred to as 'pharmacological effect similarity' or 'pharmacological similarity' in this study.

These results suggest that chemical structures similarity does not always correspond to pharmacological effect similarity.

6– 8 Drug side effect similarity has been also employed to predict drug targets.

Let schem and sphar be chemical structure and pharmacological effect similarity functions, respectively.

Campillos et al. (2008) identified new DTIs using side effect similarity.

For examples, protein similarity based on ligand-binding sites and drug side effect similarity based on the tf-idf measures would be interesting.

On the basis of this observation, Campillos et al. (2008) used side effect similarity of marketed drugs to predict drug pairs with common protein targets.

The use of side effect similarity has been recently proposed to infer whether two drugs share a target (Campillos et al., 2008).

Figure 2 shows the distributions of chemical structure similarity scores and pharmacological effect similarity scores against the network distance for drugs targeting enzymes, ion channels, GPCRs and nuclear receptors.