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A key analysis tool for determining the importance of these continuous-value biomarkers (such as level of ER staining) for determining treatment effectiveness is the Subpopulation Treatment Effect Pattern Plot (STEPP) [ 20].
Exposure to TBDD reduced spawning success, altered ovarian morphology and reduced hepatic vitellogenin gene expression, which implies that TBDD has a similar effect pattern as the chlorinated analogue.
The STEPP (Subpopulation Treatment Effect Pattern Plots) method, by investigating the patterns of treatment effects within randomized clinical trials or datasets from meta-analyses, will help to identify features that predict responsiveness to the treatments under study without the pitfalls of selective retrospective subset analysis.
The published data are very heterogeneous and do not provide a clear effect pattern for each of the materials.
Moreover, there is a qualified need for constraining the non-linear effects because particularly at the boundaries of data ranges effect pattern resulted that conflict with expert knowledge.
If these interpretive hypotheses are correct, then it is no exaggeration to say that distinguishing same and different in effect, pattern recognition or analogical extension is the core explanatory notion underlying classical Chinese philosophy of language, epistemology, and logic.
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Those who had been given the cream (the control group had nothing) showed "placebo effect patterns" in the prefrontal cortex.
We examine whether the quality of service during routine operation periods exhibits learning effect patterns.
In order to reduce the screen effect, patterning CNT is an efficient method.
Both treatment arms had the same breast symptom and systemic side effect patterns during the follow-up period.
Note that the number of possible scenarios for founder effect patterns and effect sizes across traits were too numerous to test.
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