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Conclusion: Prolonged mild hypoxemia has a differential effect on type I NOS mRNA in fetal sheep brain areas.
However, this SNP showed a negligible effect on type 2 diabetes in the European population.
Similarly genetic factors also differ in their effect on type 2 diabetes as compared to European population.
We showed SNPs from seven loci, including GIPR, TCF7L2, MADD, CRY2, GLIS3, PROX1 and SLC30A8, had an effect on type 2 diabetes in our samples.
A previous study [27] also reported these loci showed a combined effect on type 2 diabetes susceptibility and led to a younger age at diagnosis.
However, neither the combined effect on type 2 diabetes susceptibility nor the association with younger age at diagnosis was replicated in our study (data not shown).
Some are known to have an effect on type 'A' and type 'B' influenza-causing viruses.
These data indicate that commensal microflora have a modifying, disease-preventive effect on type 1 diabetes.
We prospectively examined whether Prx4 has an additive effect on type 2 diabetes prediction.
Despite these concerns, the estimated and observed ORs for the SHBG SNP effect on type 2 diabetes were very similar.
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