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The phrase "effect on the functionality" is grammatically correct and can be used in written English.
It describes the impact or influence that something has on the functioning of a system or object. Example: The latest software update had a positive effect on the functionality of the app, reducing loading times and improving user experience.
Exact(10)
We further report that such variable U-tails can have a significant negative effect on the functionality of the crRNA effector of the CRISPR-AsCpf1 system.
The concentration of nanoparticles has a great effect on the functionality of nanolubricants, with about 0.1 to 0.5 wt.% stated as the optimum concentration for nanoparticles in most of the investigation works and studies[12, 16].
Even in this case, when the RM190 was added to statistical analyses it did not show a significant effect on the percentage of explained AAC variation, confirming that this molecular marker does not have a direct effect on the functionality of the enzyme (Dobo et al., 2010).
This indicates that these point mutations have no effect on the functionality of the gene and its encoded product.
Furthermore, there was no effect on the functionality of TAA‐specific CD8+ T cells (Supporting Fig. 5B).
Thus, the data suggest that the omega-5 gliadins have a negative effect on the functionality of the flour.
Similar(50)
The fusion of INP had no effects on the functionality of GDH cofactor binding domain.
This chapter elucidates the key processing parameters of SLM and their effects on the functionality of fabricated scaffolds.
An explanation for why the GM-CSF genetic adjuvant apparently had diverse effects on the functionality of T cell responses in the blood and lung of PMED HA DNA vaccinated animals is unclear, but we hypothesize that it is likely related to different effects of GM-CSF on antigen presentation.
(284) The phosphate groups are now known to have important effects on the functionality of amylopectin, on starch mobilization and thus on the degradation of the starch granule.
Different mutations of HBx exert differentiated effects on the functionality of HIF-1 α, however, the overall activity of HBx mutants appears to increase the expression and transcriptional activity of HIF-1 α.
More suggestions(17)
effect on the suitability
effect on the effectiveness
exposure on the functionality
effect on the operating
effect on the performance
effect on the operation
effect on the role
effect on the operability
impact on the functionality
effect on the usefulness
effect on the serviceability
effect on the workability
effect on the viability
effect on the functions
impacts on the functionality
effect on the functioning
implications on the functionality
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com