Sentence examples for effect on the differentiated from inspiring English sources

Cancer stem cells have been described in MM and it has been found that hedgehog activity is present specifically within the myeloma stem cell population, resulting in enhanced proliferation of these cells while having no effect on the differentiated plasma cells.

All previous data characterizing the LIV0APOLY cells were carried out under high-glucose (HG) conditions; therefore, we investigated whether a lower-glucose (5.5 mM) concentration had an effect on the differentiated phenotype of LIV0APOLY cells (2 days postconfluence, without 4-OHT).

The nucleoside analogs 5-Azacytidine (5-Aza-CR) and 5-Aza-2'-deoxycytidine (5-Aza-CdR) both have profound effects on the differentiated state of cultured cells [1].

In contrast, L. gasseri had relatively little effect on the more differentiated HT29‐MTX sub‐clone: here the specific effect of EPA was apparent both in the presence and absence of L. gasseri.

Generally, MTX treatment inhibits proliferation of rapidly dividing cancer cells without having a limited effect on the proliferation of differentiated cells.

Daily application of 2 mg testosterone had little effect on the number of differentiated sebocytes in WT 4OHT-treated and acetone-treated K14MycER mice of either gender, confirming that testosterone did not act directly on the MYCER fusion protein.

In this study, we report that lethal toxin has a profound destructive effect on the barrier function of differentiated human airway epithelium.

While the effect on B cell differentiation has been a focus of research concerning immunotoxicity of TCDD and related compounds, its possible effect on the fate of terminally differentiated plasma cells has not received much attention.

Our current study further supports this idea by confirming that IFN-γ has a differential effect on differentiated tumour cells and TRCs, inducing the former to enter apoptosis but the latter to enter dormancy.

Despite awareness on the differentiated effects that the same infrastructural interventions may have on different groups and populations (e.g. Booth et al. 2000), infrastructures are often designed without taking much into account their splintering effects on people and spaces (Graham and Marvin 2001).

The aim of this study was to examine the effect of three-dimensional (3D) architecture on the differentiated phenotype of human smooth muscle cells derived from the stroma of the lower urinary tract.