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(3) The nature of the back contact (Ag vs. Ag|Cu) has the largest effect on the dependence of J SC on the thickness of the Cu2O layer (compare Fig. 7a, d) which is followed by V OC (compare Fig. 7b, e).
The control EMSA exhibited neither an IL-1β-induced increase in Oct-1 nuclear binding activity nor a suppressive effect on the dependence on pretreatment of the cells with ALP or hSA.
Similar(57)
Of the three mutations outside the active site face, the one lying closest to the SRL−restrictocin interface had the largest effect on the salt dependence for ribosome cleavage.
This shows that the wedge has a large effect on the directional dependence of the MHVRs.
The effects of syntaxin 1A on homomeric KCNQ2 channels resulted in both decreased current amplitudes (with no effect on the voltage dependence of activation; Fig. 2) and slower activation kinetics with increased fast (τfast) and slow (τslow) time constants, as derived from fitting with an exponential two-component Boltzmann function (Fig. 2).
Thus, the KOH salt coating has little effect on the rate dependence of CO partial pressure.
Lowering intracellular [Cl−] had the opposite effect; thus intracellular [Cl−] has a modulatory effect on the voltage dependence but does not contribute toward the gating charge movement.
Notably, l-citrulline and l-arginine had no effect on the pH dependence of either kFAD or kC4a-OOH (Table 1).
Therefore, the location of the ionizable residues relative to the aggregated regions of the SEM1 86 107) peptide may be essential for determining their effect on the pH dependence of fibril formation and dissociation.
However, mutation of residues close to the putative E S interface has a larger effect on the salt dependence than mutation of residues farther from the interface, consistent with restrictocin binding in an oriented fashion to the ribosome.
In contrast, a flecainide concentration (10 µM) which has comparable efficacy on INaL inhibition (Figure 5), has no significant effect on the voltage-dependence of F1473C channel closed state inactivation (Figure 6A, Table 1), consistent with previous reports on the effect of flecainide on steady state inactivation for WT channels[18].
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