Sentence examples for effect on the checkpoint from inspiring English sources

The experiments above suggest the possibility that combining Aurora B and Mps1 inhibitors has a more than additive adverse effect on the checkpoint.

This report describes the effect of the Checkpoints Program on driving limits and outcomes.

We also identify effects on the checkpoint response and cellular events related to DSB resection.

At several relative ratios (three of which are shown in Figure 5E), the effects on the checkpoint from combining the two inhibitors denoted a very small combination index (CI), indicative of very strong synergy between the inhibitors (CI<1 indicates synergy and CI=0.3 indicates strong synergy).

Considering that GADD45 has been shown to play a role in the control of the G2 M checkpoint (Wang et al, 1999), these results indicate that DBC1 may have an inhibitory effect on the G2 M checkpoint.

Paclitaxel/Pb-TCMC-trastuzumab treatment had the greatest effect on the mitotic spindle checkpoint proteins investigated.

Addition of hesperadin at 100 nM caused a dramatic effect on the duration of the checkpoint response, with cells being completely unable to arrest in mitosis in high nocodazole.

The same effect was also observed at 10 μM nocodazole or 15 μM colchicine, ruling out an off-target effect of the spindle poison on the checkpoint, or an effect of residual microtubules on checkpoint satisfaction (Supplementary Figure S4).

However DNA-PK inhibition did not have any significant effect on the phosphorylation profile of checkpoint proteins after NEU damage.

The radiosensitizing effect of SSd may contribute to its effect on the G0/G1 and G2/M checkpoints of the cell cycle.

The radiosensitizing effect of SSd on hepatoma cells is more obvious under hypoxia, and its mechanism may contribute to its effect on the G0/G1 and G2/M checkpoints of the cell cycle.