Sentence examples for effect on the backbone from inspiring English sources

Due to its solvophobic effect on the backbone, osmolytes force thermodynamically unstable proteins to fold without altering the rules for folding to a native-like conformation ([21], [22]).

We found that CO binding has a weaker effect on the backbone NH dynamics of F97Y HbI than on those of WT HbI, implying that the internal dynamics contribute to the cooperative binding of carbon monoxide.

In contrast, much stronger effects were observed when IL-8 was titrated with CS4 (B), CS6 (C) and DS (D) indicating that the negatively charged sulfate group of CS or DS has a pronounced effect on the backbone structure of residue E75 of IL-8.

At the same time, the side chains collectively favor transfer to water (6 × (−0.875) ≅ −5.3 kcal/mol), tending to cause some Rh expansion of the DSE, but this is overridden by the +18.3 kcal/mol effect on the backbone (see Table 2 and Figure 5A).

In order to study the tacticity effect of the backbone on the thermotropic properties of side-chain liquid crystalline (SCLC) polymers, the synthesis of four polymethacrylates with different tacticities and bearing methoxy biphenyl mesogenic groups was carried out.

The WAXD data showed that POSS formed aggregation instead of crystallization in the polymer matrix, indicating the significant effect of the backbone constraint on POSS crystallization.

We synthesized an ODN2006 sequence consisting of either a PD or PTO backbone PD-ODN20066 PTO-ODN20062006, respecTabley) (Table 1) and examined the effect of the backbone composition on NF-κB activity.

In addition, the mutation V32P within the signaling motif-N (at a position not directly involved in H-bonding) also resulted in slightly reduced activity, presumably due to effects on the backbone conformation and/or flexibility of the β-strand.

35 Either way, the result revealed that the spectral separation of s-IBM protein assemblies labeled with p-FTAA was not attributable to conformational diversity of tau, thus suggesting that the effect on the thiophene backbone conformation and conjugation length upon binding is not determined by tau only, but instead the collective assembly of misfolded proteins.

The absence of any detectable chemical shift perturbation for residues 13 140 upon losing the positive N-terminal charge indicates that the acetylation has no discernible effect on the time-averaged backbone angles of these residues, highlighting the absence of specific interactions between the C-terminal region and the N-terminus.

The boundary conditions effects on the fundamental backbone curves for FG AL/AL2O3 isosceles triangular plate are investigated in Fig. 5.