Sentence examples for effect on specificity from inspiring English sources

Detection of other methylated markers in stool DNA improved sensitivity with little effect on specificity.

One can therefore experimentally alter the specific binding site or its competing sites, as well as the transcription factor, by point mutations and then observe the effect on specificity, e.g. by measuring the expression of upstream genes.

A study of untreated culture-confirmed cavitary pulmonary tuberculosis patients in Turkey also found that reducing the cut-off to between 0.05 and 0.10 IU/ml improved sensitivity with little effect on specificity [22].

We could only report the sensitivity; its effect on specificity was unknown and needs further investigation.

The effect on specificity (Fig. 2B) is more modest, and increasing the values beyond 30 has only a limited effect.

Prevalence of inflammatory bowel disease had no effect on specificity, just as with the exclusion of patients with rectal bleeding.

Using data from more than one dataset offers the opportunity to identify more cases, albeit with uncertain effects on specificity and PPV.

Various detailed kinetic schemes have been suggested and their potential effects on specificity have been discussed – however without direct relation to concrete conformational mechanisms.

The krel (SRL) data in Figure 3A do not differentiate between effects on specificity and on basal endoribonuclease activity.

Full substitution of adenosine by DAP showed varied effects on specificity in the four different probe sequences.

20 Whiting et al 39 found, in their systematic review about sources of variation and biases on diagnostic accuracy of diagnostic instruments, that sensitivity increased with disease prevalence and severity, whereas the effects on specificity were inconsistent.