Sentence examples for effect on pathology from inspiring English sources

This would be likely to have its most profound effect on pathology during early embryogenesis when the eye is forming and COL2A1 is first expressed.

However, in this model deletion of ATF4 alone had no effect on pathology.

These inflammatory cytokines are therefore necessary for the virus susceptibility-gene effect on pathology in the DSS-induced colitis model.

However, the magnitude of the change required for a beneficial effect on pathology is unknown and perhaps the levels of rescue achieved meet a therapeutic threshold.

Further evaluation of the relationship between chronic inflammation and the tract-specific effects on pathology using this novel imaging/histological strategy may provide valuable insight into the mechanism of tract-specific degeneration observed in this study.

More than a decade after the initial reports of positive effects on pathology and cognition produced by Aβ immunization in TgAPP mice [ 114], it is now well established that reduction of plaque volume and restoration of functional deficits in TgAPP mice can be achieved by both passive and active Aβ immunotherapy [ 56].

Thus, S14G-HN showed no effect on tau pathology at least at the early plaque-bearing stage.

However, the immune response and its effect on lung pathology may decrease the drug responsiveness of the bacilli.

After this initial phase of granuloma development, a CD4+ cell response begins to exert a dominant effect on the pathology and the requirement for B cells is alleviated.

This study showed that both total amount and phosphorylation status of tau were unaffected by S14G-HN treatment in 3xTg-AD mice (Fig. 7), suggesting that HN has no effect on tau pathology.

Interestingly, although carnosine was able to reduce the amyloid load, the treatment produced no decreases of phospho-tau immunoreactivity in the 3xTg-AD CA1 subfield (Figure 3E-H), indicating that the peptide has no effect on tau pathology.