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Moreover, the combination of anticancer drug paclitaxel (PTX) and siMDR1 loaded HSPCs showed synergistic effect on overcoming MDR, which inhibited cell growth and induced cell apoptosis.
This might be the plausible explanation that knockdown of AKT1 expression has the better effect on overcoming chemoresistance than only inhibition of AKT1 activities.
Inoculum concentration had a more pronounced effect on overcoming the inhibition of LCFAs than that of calcium ion, while calcium ion plays a role only when inoculum concentration met a threshold level.
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NusG at 100 nM had similar partial effects on overcoming the H-NS-stimulated pauses.
To estimate the effects of overcoming sleepiness on the prefrontal activities corresponding to each WM task level separately, we analyzed Pearson's coefficients between change in SSS level and change in oxy-Hb concentration for each channel on the 0- and 2-back tasks separately.
To estimate the effects of overcoming sleepiness on the prefrontal activities corresponding to WM characteristics, we analyzed Pearson's coefficients between change in SSS level and the difference of change in oxy-Hb concentration for each channel on the 0- and 2-back tasks.
Inhibition of CDT2 arrests ovarian cell proliferation and might mediate the effect of MLN4924 on overcoming cisplatin resistance (Birner et al, 2012; Pan et al, 2013).
The last feature may in part be due to possible effects of ALMP participation on overcoming cultural barriers to labour market integration.
We focus on overcoming the effects of a changing pose of the speaker, a problem encountered in natural situations where the speaker moves freely and does not keep a frontal pose with relation to the camera.
In this context, current efforts focus on overcoming the effects of potent neurite growth inhibitory factors in the adult CNS [ 24] or providing the growth promoting cues to immature neurons [ 12, 13] before, during, or after standard dissociated cell transplantation.
The effect of richly supplemented U-medium on overcoming the developmental arrest at the globular embryo stage might be analysed by studying expression of the early responding genes GST, POX and chitinase in response to supplementation of the standard medium with individual compounds of the U-medium.
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