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The generality of this stability-function tradeoff must be viewed within the context of the fact that regardless of their effect on functions most mutations are destabilizing [21], [22], [23], [24].
Using both TCP and ASA has a protective effect on functions of central nervous system.
Therefore, it would be interesting to examine whether cancerous mutations of NPM have an effect on functions of C/EBPα in the control of cell proliferation and growth.
However, strumpellin disease mutations do not affect its incorporation into the WASH complex or its subcellular localisation, nor do they have a dominant effect on functions of the WASH complex, including regulation of endosomal tubulation, transferrin receptor traffic or β-2-adrenergic receptor localisation.
Similar(56)
However, there is still a lack of evidence supporting its effect on function.
The mutation of 61Tyr-->His diminished function but changes 61Tyr-->Ala and 61Tyr-->Phe had no effect on function.
Although normal propagation through interstitial interaction is unlikely, the magnitudes of the electrotonic interactions were large and may have a substantial modulating effect on function.
For many patients, the chronic neuropathic pain has a profound adverse effect on function and quality of life.
It also has a profound effect on function.
2 No effect on function provided by IPA.
Genotype-specific gene expression studies will shed light on the allele-specific effect on function.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com