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Compared with rabdoternin B, maoecrystal I displayed a more potent effect on cell cycle arrest.
The effect on cell cycle phases and mitochondrial membrane permeability was analyzed through flow cytometry.
Void nanoparticle had no effect on cell cycle progression as compared to native cells and thus is nontoxic in nature.
This caused a 30% reduction in fork number, but no significant effect on cell cycle distribution or viability.
Therefore, white medium culture conditions do not trigger any irreversible effect on cell cycle and gene expression.
Therefore, we focused our investigation on Pep-7's effect on cell cycle in the current study.
It should be noted that PHE or PRA alone have no effect on cell cycle phases (Supporting Information, Figure S1, D).
In order to understand the effect of the BPs on breast cancer cell viability, we evaluated their effect on cell cycle progression (Fig. 3).
In addition, celastrol induced G2/M arrest (Fig. 3A) that was consistent with an earlier report [29], further demonstrating celastrol's effect on cell cycle arrest.
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The results showed that mercury ions have no effect on cell-cycle kinetics.
Its effect on cell-cycle was confirmed by inhibitors, a knockout strain and the action of recombinant L-asparaginase on cell lines.
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