This facilitates investigation of the functional effect of a spectrum of drugs on representative cell models and may be developed as a tool for cancer diagnostics and personalized medicine in the future (Barretina et al., 2012, Garnett et al., 2012, Pemovska et al., 2013, Shoemaker, 2006, Tyner et al., 2013, Yang et al., 2013).
To determine the target biological pathways for each small molecule, we developed a novel framework for encoding small molecule effects on a spectra of biological processes or GO functions that are enriched in the differentially expressed genes of a given small molecule perturbation.
Mutation RS V108 is a strong indicator of poor response to AZT, DDI, 3TC, and AZT, 3TC combination at 8 weeks (SD classification) whereas RS M36 has a negative effect on a larger spectrum of drug combinations.
Nutritional strategies in intensive care units, as evaluated in this randomised trial of initial trophic versus full enteral feeding, had no effect on a wide spectrum of outcome measures reported by patients, with no differences between groups for the physical function primary outcome or for nearly all secondary physical, psychological, cognitive and employment outcomes.
Changing s has a profound effect on all spectra.
The speeds are known as redshift velocities, for their effect on a galaxy's spectrum.
Dietary fibers, such as pectin, have been shown to have positive effects on a wide spectrum of pathological conditions.
It has been proven to reduce the incidence of type 2 diabetes and hypertension in people with IGT [ 7, 20]; in addition, studies in both prediabetes and type 2 diabetes populations have demonstrated that the use of acarbose is associated with reductions in cardiovascular events [ 20, 21] and with beneficial effects on a broad spectrum of CV risk factors.
We have confirmed this by simulating clutter echoes and evaluating their effect on the spectrum of an echo coming from a target at zero azimuth and zero elevation.
To test the influence the lancets have on the reduction of clutter, we simulate their effect on the spectrum of an object at zero azimuth.
