Taken together the data suggest that the model is helpful in understanding likely effects of various agents in migraine.
In order to investigate the effects of various agents on phenylephrine hydrochloride (PE -induced contraction, when a steady contraction induced by PE -inducedl/L) was reacontractionus agents (3 × 10−4 mol/L) whenadded to the organ bath.
Bill had already been hard at work in Merck's Therapeutic Research institute for nearly a decade, applying his efforts to understanding the effects of various agents on a wide range of parasitic organisms, mostly worms.
We examined the synergistic effects of various agents, including differentiation inducers and rapamycin, on growth inhibition of cells of breast cancer cell line MCF-7.
This is in line with the study duration of other trials that investigated the effects of various agents on CIMT [ 18– 218.
Our laboratory has extensively utilized the rodent dorsal skin flap window chamber model in determining real-time, sequential angiogenic effects of various agents (Li et al, 2000).
Investigation of the effects of various agents on granulosa in vitro is dependent on the follicle stage at which the cells were isolated and the composition of the culture medium.
Measurement of the activity of extracellular released LDH is a very suitable routine assay for evaluating the cytotoxic effects of various agents, including chemicals or bacteria, on eukaryotic cells [ 35, 36].
To identify the source of ROS generation, we evaluated the effects of various agents (an antioxidant, N-Acetyl L-cysteine (NAC), and a mitochondrial complex I and Nox inhibitor, diphenylene iodonium, DPI) on GC cells.
Furthermore, so-called evidence-based guidelines may be limited in their ability to be more prescriptive given the lack of clinical trial evidence from properly conducted long-term RCTs comparing the effects of various agents on clinically important outcomes.
