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Comparing the results of different scenarios for vaccine uptake and temperature (Figure 3A,B) indicated that both vaccine uptake and temperature had a significant (P<0.001) impact on outbreak size, but that the effect of uptake depended on the temperature data-set (i.e. there was a significant (P = 0.006) interaction between uptake and temperature).
These results are in agreement with the predictions of Watanabe et al. for the effect of uptake transporter activity on plasma and liver concentration of pravastatin.
Cox proportional hazards regression models were used to examine the effect of uptake parameters as continuous variables, and to estimate hazard ratios (HRs).
The EI, a normalized measure of sensitivity, for the effect of uptake transporter activity on muscle AUC exactly matched with that of the plasma AUC.
Taken together, direct measurement of NA uptake and effect of uptake blockers, an age-related increase in stimulation-evoked fractional NA release in peripheral adrenergic nerves is not explained by an age-related change in the function of NA transporters.
To allow analysis of the effect of uptake sequence accumulation on the bacterial proteomes, we restricted our study to the perfect-consensus core 9-bp USS and 10-bp DUS sequences.
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JNK inhibition had no effect on uptake of any strain or form of S. aureus.
In this report, we analyze the reciprocal effects of uptake sequence accumulation and selection on bacterial genomes and proteomes.
Two further analyses examined the within-gene effects of uptake sequences, asking first whether uptake sequences are more common in less conserved parts of proteins and then whether uptake sequences interfere with optimal coding and thus might reduce fitness.
The authors concluded that PS microparticles had a relatively limited effect on uptake of PCBs by A. marina.
Diets enriched with Lemon balm and Sage, rich in polyphenol, have the most positively pronounced effect on uptake of metals.
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