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Using both methods, we found no significant associations between TRS and respiratory admissions for any group, but the case-crossover results suggested there might be a delayed effect of TRS on the younger age groups.
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Almost 20 g of the catalyst was placed inside the reactor to examine the effect of TR on the performance of the catalyst.
We have examined the effect of TR on the growth of capillary endothelial cells in vitro.
Following the observation that TR induces apoptosis in endothelial cells, we examined the effect of TR on angiogenesis.
Following the observation that copper reversed the inhibitory effect of TR on endothelial cells, we thought that TR effect might be via SOD-1.
We have shown that TR strongly inhibits SOD-1 activity and that exogenously added copper and not Zn2+, Ni2+, Fe2+ or Mn2+, was able to out-compete the inhibitory effect of TR on endothelial cell growth.
Both endothelial cell types were 10 60-fold 10 60-foldtive to the inhibitory effect of TR on DNA synthesis than other cell types such as BALB/moreeratinocytesensitive glioma cells, D122 Lewis lung carcinoma or BSMC.
To test the effects of TR on CTCF mediated enhancer blocking, we mutated the two half sites of the F2 element, which is characterized by an everted palindrome spaced by 6 nucleotides.
All plasmids containing TR were also constructed in the reverse orientation in the reporter to examine the effect of TR orientation on gene expression.
At the same time, as shown above, we observed a significant effect of TR feeding on mTORC1activity in both liver and spleen.
Two of the largest screens of the effect of TR variation on phenotype have been the examination of 37 TRs in 17 dog genes (Fondon and Garner 2004), and the examination of 33 random TRs in promoter regions of an equivalent number of yeast genes (Vinces et al. 2009).
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