Sentence examples for effect of these variant from inspiring English sources

The next great challenge of pharmacogenetics is to pin down the cellular location and effect of these variant proteins on the pathways and networks that govern individual variation in responses to drugs and other exogenous chemicals.

Given the availability of smoking measures in our sample, we also tested if an effect of these variants on smoking quantity (CPD) or nicotine dependence (FTND) was detectable in our sample.

Subsequent studies of the effect of these variants on estimates of the beta-cell function and insulin sensitivity have been inconclusive.

Hence, investigating the effect of these variants in combination with other genetic variants or environmental factors would help elucidating their potential role in NAFLD.

In addition, because esophagitis typically presents 4 6 weeks following initiation of radiation therapy, we also analyzed the effect of these variants using logistic regression.

However, overall there is ambiguity regarding the effect of these variants and in our previous study none of them were associated with either trait [3].

We aimed to examine the potential effect of these variants on fetal body composition by investigating the variants in relation to birth weight and ponderal index of the newborn.

It may be possible to investigate the aggregate effect of these variants, for example Purcell et al. [22] showed a large number of SNPs (with p values up to 0.5) from a schizophrenia GWAS demonstrate predictive power collectively.

These associations may reflect an as yet unknown biological effect of these variants.

The effect of these variants at the time of ICU admission remained significant in Cox regression.

Our study had limited power to estimate the effect of these variants on eGFR.