We tested the effects of the compartments, follicle stages, and their interactions on gene expression using nbinomGLMTest.
Intriguingly, in spite of the fact that both ionomycin and A23817 have an identical activity, transport of Ca2+ across the membranes of eukaryotic cell compartments, the effect of these inhibitors on the P. falciparum transcriptome was not identical.
To properly model the effect of compartments, the localization of enzymes and the transport of metabolites need to be determined.
Also, the inclusion of medicated subjects who remained on medication for the duration of the study period may have muted any effect of AT compartment change on the metabolic marker.
The bin-swapping procedure had the effect of rendering compartment-specific information irrelevant, and was undertaken to see whether there was any such information present, implicitly, in the raw data.
A 2-way ANOVA of compartment type against remapping condition showed a main effect of compartment type [ F3,48 = 8.50, P < 0.001] and a significant interaction of trial type against compartment [ F6,48 = 5.97, P < 0.001].
The results of the peak rate analysis are shown in Figure 9 C, D. A 2-way repeated-measures ANOVA of compartment against trial type revealed no effect of compartment [ F3,6 = 1.16, NS] but a main effect of trial type [ F2,6 = 3.86, P < 0.05] and a significant interaction [ F6,228 = 6.67, P < 0.001].
A 2-factor (day and compartment distance) repeated-measures ANOVA revealed a main effect of compartment distance [ F2,64 = 15.1, P < 0.001, but no main effect of day or significant interaction.
We first investigate the (I_{mathrm{Pump}} -based mechanI_{mathrm{Pump}} -basedlar burst generated by the voltage comechanism throunderlyingrcathen analysis and then study the effect of the calcium comparegularon the resulting burstcation structures to understand how the transition from regeneratedsts to the long byrstheappens.
These tissue slide-based studies for the first time evaluated the effect of the tumor compartment on the diagnostic and prognostic value of altered miRNA expression.
