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The effect of the lead compounds 1e and 2c on the cancer cells tested was associated with cell cycle arrest in the G2/M phase.
The main reason could be the framing effect of the lead time or total tradable time used.
Herein, we have further investigated the effect of the lead compound SPP86 on RET mediated signaling and proliferation.
Indirect effects should be considered in this observational study, such as the possible effect of the lead time of earlier diagnoses on estimated mortality hazard ratios.
An analysis conditioning on the effect of the lead SNP (rs4807216) revealed an additional low-frequency SNP (rs2385821) at genome-wide significance (Table 1).
To further explore whether the effect of the lead SNP rs651007 was driven by ABO blood group, we introduced ABO blood group into the multivariable linear regression model.
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Art historians already suspect that Goya and Van Gogh may have suffered from the ill effects of the lead in their paints, which can cause depression, pain and personality changes.
Compared with the growth inhibitory effects of the lead structure vatalanib, the antiproliferative effects of our novel compounds were much more pronounced, especially in the TGCT cells.
In this case, we may want to study the effect of the first lead of the main explicative variables.
The size effect of the CNT leads to an electric field enhancement within the device.
Thus, an antioxidant effect of the extract leads to a protection on gastric tissue.
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