They improve the therapeutic effects and reduce the side effects of the formulated drugs.
Such a nanoparticle system for drug delivery is multifunctional, which provides a platform to formulate anticancer drugs which reduces the side effects of the formulated anticancer drug, promotes synergistic therapeutic effects, and achieves targeted delivery for the therapy.
In addition, TPGS-emulsified nanoparticles have been shown higher drug encapsulation and cellular uptake, longer half-life and higher therapeutic effects of the formulated drug than those emulsified by poly (vinyl alcohol) (PVA), a widely used emulsifier in nanoparticle technology [21].
In this line, it is anticipated that biodegradable polymer-based nanocarriers can provide a way of sustained, controlled, and targeted drug delivery to improve the therapeutic effects and reduce the side effects of the formulated drugs [ 1, 11, 12].
The therapeutic effect of doxorubicin formulated in the CNPs (with folate targeting effect) was also evaluated in vitro by measuring the viability and the extent of apoptosis of human retinoblastoma cells (Y-79).
Pronounced positive effects of the liposomal formulated curcumin analogue on survival of HL60 xenograft mice would render this molecule a potent clinical candidate against leukemia alone or in combination with other antineoplastic agents.
The aim of this work was to examine the effect of mupirocin, formulated in liposomes, against S. aureus biofilms.
Design of experiment using full factorial method was employed in the process of cutting fluid formulation, while the effect of formulated cutting fluids on surface roughness and cutting force in turning AISI 4340 steel with coated carbide using Taguchi method were investigated and compared with conventional (mineral) oil-in-water emulsion cutting fluid.
We examined the effect of 2% topical formulated fruit cream on the wrinkles of crow's feet site of the eyes.
This review aims to clarify the mechanisms governing the satiating effect of gums in formulated foods, update the information and draw attention to points that require further investigation.
