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We could sometimes see the immediate effect of the excessive use of cannabis, or the other drugs then in fashion, but we did not know in the least what would happen next, whether cannabis itself (as turns out to be the case) might have long-term consequences, or whether it would lead inexorably to the use of heroin.
At the same time, the PV of the growing film was further enhanced (see Figure 2b) because of the ion bombardment effect of the excessive H species.
The cell death observed with Sdhaf1 knockdown is an expected effect of the excessive ROS produced by the disassembled Sdha subunit.
In most cases, the effect of the excessive postnatal body weight on early AAM is a consequence of IUGR or SGA [ 75].
The deleterious effect of the excessive production of these WRKYs during plant growth suggested that the expression of this gene might require proper regulation during the activation of plant defense responses.
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Half a century ago the philosopher Leo Strauss remarked that the passage in which the Declaration of Independence proclaims its self-evident truths "has frequently been quoted, but, by its weight and its elevation, it is made immune to the degrading effects of the excessive familiarity which breeds contempt and of misuse which breeds disgust".
In addition, mutations of sod2/3 or the redox regulator daf-16 abolished the negative correlation between ROS and paraquat levels, suggesting major effects of the excessive response was contributed by the antioxidant system (Ren et al., 2017).
In ALD, the toxic effects of the excessive very long-chain fatty acids are thought to result from an increase in steady-state ROS production, depletion of GSH and dysregulation of the cell redox homeostasis (38, 39).
However, the effect of excessive methionine on the development of the cranial growth plate is unknown.
The effect of excessive androgens on the activity of the GnRH pulse generator has been explained in part [21], [24].
The effect of excessive androgens on the activity of the GnRH pulse generator has been analyzed [24].
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