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We fixed the effects of the two confirmed SNPs as 0.3 and 0.2 standard deviation of residuals (SD) and varied the effect of the candidate SNP from 0.04 to 0.2 SD.
In order to evaluate the functional effect of the candidate Suppressive miRNAs on the aggressive features of melanoma, we cloned and stably over-expressed them in HAG cells to evaluate their effect in-vitro and in-vivo.
Thus, the assessment of the effect of the candidate variables on the risk and the level of OPG excretion should adjust for the use of toltrazuril treatment.
In such studies, the GLM developed here can be applied to estimate and confirm the effect of the candidate gene on the trait of interest.
Significance of the effect of the candidate SNP was evaluated in an animal model with ASReml3.0 [ 31], by fitting the SNP genotype as a fixed class effect.
We observed no effect of the candidate gene haplotypes on a range of aggression-related phenotypes, thus extending our conclusions to several types of aggressive behavior.
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We predicted the effect of the candidates (Table 2), and we found a candidate causing a premature stop codon in the gene At5g55580 making this a very likely cause for the phenotype.
We identified the key safety issues and have investigated the neutron-induced irradiation effects of the candidate coating/hohlraum materials using the radiation chamber conditions of the ARIES-IFE dry wall concept.
To assess the effects of the candidate SNPs specifically on glucose-stimulated insulin secretion, we analysed data obtained from an IVGTT in a subgroup of 150 subjects.
The effects of the candidate gene polymorphisms were analyzed in two ways.
Additionally, it is possible that some of the genetic effects of the candidate loci are context-dependent.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com