This illustrates the effect of using blind distance-based routing and not taking into account network condition.
For one trial that evaluated the effect of a blind versus open design on retention this was not applicable.
Comparison of clinical outcomes between blind and non-blind trial for all randomised women was performed (the intention-to-treat analysis for the effect of blinding), using the Cox proportional hazards modelling.
How much of this results from selection bias for women with different background characteristics, from difference in seeking medical advice due to health symptoms because of knowing the treatment or not, or from a delay in diagnoses due to the effect of blinding on the attitudes of physicians and patients needs further research.
For one trial, a judgement about blinding was not applicable because the study evaluated the effect of blind versus open trials on retention (Avenell 2004).
For instance, nine studies looked at the effects of blinding the reviewers to the authors or vice versa, but none found much difference in quality.
These measurements are laborious, and it is desirable to develop simple models, that could be used for product development to estimate the effect of changing the properties of the blind material and its design, without the need to make detailed measurements on each variation.
For detail of the exploration of the posterior cluster (labeled pdATL in Fig. 2a), which does not show an activation pattern consistent with an overall effect of imperceptibility in the blind, see Supplementary Notes and Supplementary Figure 6.
Specifically, when inspecting this superior ATL imperceptibility cluster in the data from Experiment 2, it showed a main effect of imperceptibility in the blind (F 1,11) = 8.63, p < 0.05; see sampled data in Fig. 2d), a significant preference for imperceptible concepts, but no domain effect (p > 0.4) or interaction (p > 0.61).
To compare the effect of blind design (active drug and placebo) and nonblind design (active drug and no treatment) on recruitment.
